Protein Design Using Continuous Rotamers
نویسندگان
چکیده
منابع مشابه
Protein Design Using Continuous Rotamers
UNLABELLED Optimizing amino acid conformation and identity is a central problem in computational protein design. Protein design algorithms must allow realistic protein flexibility to occur during this optimization, or they may fail to find the best sequence with the lowest energy. Most design algorithms implement side-chain flexibility by allowing the side chains to move between a small set of ...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2012
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1002335